• Pediatric Stem Cell Transplant Clinical Trials

    Our scientists are recognized for their discoveries surrounding stem cell biology and blood formation. One of our research breakthroughs is the discovery that fat cells in bone marrow suppress the recovery of blood cell production following a stem cell transplant (also called bone marrow transplant) in mice. We are now investigating the use of autologous transplants (self-donation of stem cells) for children with neuroblastoma (a cancerous tumor that begins in nerve tissue) and brain tumors, unrelated donor transplants for patients with sickle cell disease, and the long-term consequences of transplants, including pulmonary function and bone health.

    Our Stem Cell Transplant Center offers unique access to a range of clinical trials in which children with rare or hard-to-treat conditions have access to innovative treatments that may help where traditional options fail. Our physicians work collaboratively with national research groups, including the Children’s Oncology Group, the Blood and Marrow Clinical Trials Network and the Pediatric Blood and Marrow Transplant Program, to develop innovative clinical trials and expand transplantation for new conditions. 

    Learn about our current studies below. To inquire about clinical trials, email us at clinicaltrials@danafarberbostonchildrens.org and read our clinical trial FAQ for answers to general questions.

    ChristineDuncanChristine Duncan, MD of the Stem Cell Transplant Center multiple national committees dedicated to advancing the effectiveness of stem cell transplants, including The Center for International Blood and Marrow Transplant Research (CIBMTR), and The Late Effects Task Force of the Pediatric Blood and Marrow Transplant Consortium.
  • Clinical Trial FAQs

    Get answers to common questions about clinical trials: What are clinical trials? Is a clinical trial the right choice for my child?
  • Clinical Trials

    Through clinical trials and research, we are learning how to use stem cell transplant in more innovative and effective ways.callout bg