Large cell lymphoma is a type of non-Hodgkin lymphoma that can develop in lymph tissue in the skin, tissues under the skin, bone marrow and spinal fluid, gastro-intestinal track, spleen, liver and lungs as well as lymph nodes. There are several subtypes of large cell lymphoma, the most common in children are:
Patients with large cell lymphoma are treated at Dana-Farber/Boston Children's Cancer and Blood Disorders Center through our Lymphoma Program. Continue reading to learn more about large cell lymphoma or visit the Lymphoma Program homepage to learn about our expertise and treatment options for this condition.
Large cell lymphomas can take anywhere from a few days to a few weeks to many months to progress. Among the common symptoms of these lymphomas are:
A timely, accurate diagnosis is critical, as large cell lymphomas can grow quickly. The most common way to find out the exact kind of lymphoma is a biopsy to obtain tissue from an affected site, such as an enlarge lymph node.
Once the diagnosis of large cell lymphoma is known or suspected, tests are done to determine the where the lymphoma is in the body. This is also known as “staging”. Common tests include:
Other tests that may be done include:
Blood tests and other tests such as an echocardiogram may be done as part of preparation for treatment but are not usually done to stage the lymphoma. After all necessary tests are completed, doctors will be able to outline the best treatment options, including clinical trials if any are available.
Treatment of large cell lymphoma depends on your child’s situation.