• Pediatric Hematologic Malignancies Clinical Trials

    Through research and clinical trials, we are working to improve current therapeutic approaches and outcomes for children with hematologic malignancies. We lead an internationally recognized clinical trials consortium for children and adolescents with newly diagnosed acute lymphoblastic leukemia - the DFCI ALL Consortium - consisting of 9 institutions in the United States and Canada. We are a founding member of a small national consortium of leading medical centers that investigate new treatments for children with Hodgkin lymphoma, including innovative drug combinations (and reduced exposure to radiation) that deliver results with fewer long-term complications. In addition, we participate in clinical trials conducted by the Histiocyte Society for patients with Langerhans Cell Histiocytosis.

    To inquire about clinical trials, email us at clinicaltrials@danafarberbostonchildrens.org and read our clinical trial FAQ for answers to general questions.

    Featured Trials

    To learn more about how Everolimus works in combination with other drugs which are commonly used to treat relapsed acute lymphoblastic leukemia (prednisone, vincristine, PEG-asparaginase, and doxorubicin). The main goal of the study is to evaluate the side effects of this treatment combination in order to determine a safe dose of Everolimus which can be given with these other 4 drugs. PI: Lewis B. Silverman, MD 

    Dr. Lewis Silverman Learn whether the side effects and drug levels of SC-PEG given in the vein every 3 weeks are similar to Oncaspar given into the vein every 2 weeks. The study will also help to determine whether changing treatment for ALL patients with high levels of minimal residual disease after one month of chemotherapy may improve cure rates. PI: Lewis B. Silverman, MD 


    Search Trials by Condition

    Search trials by condition using the links below, or download a summary of all current trials at Dana-Farber/Boston Children's Cancer and Blood Disorders Center.
  • Clinical Trial FAQs

    Get answers to common questions about clinical trials: What are clinical trials? Is a clinical trial the right choice for my child?
  • Know Your Options

    Not sure which clinical trials might be right for your child? Email our clinical trials team at clinicaltrials@danafarberbostonchildrens.org.
    We can help you navigate your options.
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