• Steroids (Prednisone) for ITP

    Prednisone/Prednisolone may also be called Colisone, Deltasone, Liquid pred, Meticorten, Orasone, Pediapred, Prelone, Prednisone Intensol, Prednicen-M, Sterapred, or Winpred. It can be used to help treat immune thrombocytopenia (ITP).

    How does prednisone help in ITP treatment?

    Prednisone/Prednisolone is thought to slow the removal of platelets by the spleen and liver and temporarily lower the level of anti-platelet antibodies. Prednisone/Prednisolone may also stabilize the blood vessels, lowering the risk of bleeding.

    General Prednisone/Prednisolone Instructions

    • The amount of prednisone/prednisolone varies for each patient. Your child's doctor or nurse practitioner will prescribe the amount based on your child's weight. Be sure that you understand the plan for giving this medicine to your child.
    • Follow the directions given to you by your child's doctor or nurse practitioner. The amount you give your child may change based on your child's platelet count.
    • Your child's doctor or nurse practitioner will make a special schedule for stopping the medication. This is called a taper. Do not stop this medicine suddenly.
    • Ask your pharmacist for a special measuring spoon for liquid medicine.
    • Shake the liquid well before each use to mix the medicine.
    • Liquid medicine can be added to 1 tablespoon of formula, milk or juice to improve the taste. Give the medicine right after mixing it with food.
    • Tablets can be crushed and mixed with any sweet soft food, such as applesauce, ice cream or baby food.
    • Give tablets (pills) or capsules with a full glass of water or milk.
    • Give prednisone/prednisolone with food or milk to decrease stomach upset.

    What should I do if I miss a dose?

    • If your child misses a dose of prednisone, please call your child's doctor or nurse practitioner. He or she will tell you when to give the next dose.
    • If your child vomits (throws up) within 15 minutes after taking prednisone, give him/her another dose. If more than 15 minutes have passed, do not repeat the dose because the medicine will have already started working.
    • If vomiting continues, call your child's doctor or nurse practitioner.

    What are the possible short-term side effects of prednisone/prednisolone?

    • upset stomach
    • nausea
    • vomiting
    • increased appetite, weight gain and fluid retention, full or round "moon" face
    • irritability
    • excitability
    • Other side effects not listed may also occur. If you notice any other effects, check with your child's doctor or nurse practitioner.

    What are the possible long-term side effects of prednisone/prednisolone?

    • increased blood pressure
    • increased blood sugar and sugar in the urine,
    • less resistance to infection and longer time for healing
    • weak bones, fractures
    • cataracts
    • delayed growth

    When should I call the doctor or nurse?

    Call if your child:

    • has symptoms that get worse or do not improve;
    • develops nausea, an upset stomach, or vomiting;
    • has been exposed to chicken pox and has not yet had this infection;
    • has any black bowel movements (a sign of bleeding);
    • has an increased thirst or urination;
    • misses a dose of prednisone/prednisolone;
    • refuses to take the medicine.

    Special safety tips

    • Contact your poison information control center if your child receives an accidental overdose at 1-800-222-1222.
    • Before giving this medicine, tell your child's doctor or nurse if your child has any allergies or other medical problems or if your child has been exposed to chicken pox and has not yet had this infection.
    • Tell your child's doctor or nurse about any other medicine your child is taking, including non-prescription drugs.
    • Women who are pregnant or breastfeeding should tell their doctor or nurse.
    • Tell doctors, dentists, surgeons and others who provide medical care for your child that he or she is taking this medicine.
    • Do not give this medicine to anyone else.
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