Ganglioglioma is low-grade tumor of mixed cell type. It is a type of brain tumor that contains properties of both glial cells (responsible for providing the structural support of the central nervous system) and neuronal cells (the functioning component of the central nervous system). It is very rare.
Children and adolescents with ganglioglioma are treated at Dana-Farber/Boston Children's
through the Brain
Tumor Center, one of the largest and most experienced pediatric brain tumor
treatment programs in the world. Our brain tumor specialists have
extensive expertise in treating all types of brain tumors, including ganglioglioma. Our patients receive care from neuro-oncologists, neurosurgeons, neurologists, and pediatric subspecialists.
Since gangliogliomas grow relatively slowly, a child may have been having symptoms for many months prior to diagnosis, or symptoms may appear more suddenly. Many children with gangliogliomas first present with seizures. Other symptoms are associated with increased pressure in the brain, including:
Common ganglioglioma symptoms may include:
Ganglioglioma symptoms may resemble those of other conditions or medical problems. Always consult your child's physician for a diagnosis.
A physician may order a number of different tests to best diagnose the tumor. In addition to a physical exam, medical history and neurological exam (which tests reflexes, muscle strength, eye and mouth movement, coordination and alertness), those tests may include:
After all tests are completed, doctors will be able to outline the best treatment options.
A child’s physician will determine a specific course of ganglioglioma treatment based on several factors. Some therapies will treat the tumor while others are intended to address complications of the disease or side effects of the treatment.
Ganglioglioma treatments include:
Specific ganglioglioma treatments will be determined by your child's physician based on:
The recommended treatment for progressive or recurrent ganglioglioma is radiation therapy. Clinical trials and experimental therapies are also available for children with recurrent tumors that are not responsive to standard therapies.
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