Adamantinomas are slow-growing cancerous bone tumors that form primarily in the tibia (shin bone), but occasionally in the jaw, forearm, hands or feet. About 20 percent of the time, these tumor spread to the lungs or nearby lymph nodes.
These rare tumors, which most often affect teenage boys and young men, usually occur after bones stop growing and require aggressive treatment. While there is no known cause, patients with adamantinoma have usually sustained trauma to the affected area.
Children and young adults with adamantinoma are treated at Dana-Farber/Boston Children’s Hospital Cancer and Blood Disorders Center through our Bone & Soft Tissue Program. Continue reading to learn more about adamantinoma or visit the Bone & Soft Tissue Program homepage to learn about our expertise and treatment options for this condition.
The symptoms of adamantinoma may appear over a short period of time or may occur for six months or more. The most common are:
In most cases, an injury brings a child to the doctor, where an X-ray may show a bone abnormality. In addition to a physical examination, other diagnostic procedures include:
After all tests are completed, doctors will be able to outline the best treatment options.
The best treatment option for adamantinoma is surgery because these tumors don’t generally respond to chemotherapy or radiation therapy. Surgery may include:
Lindsay Frazier, MD, explains how a multidisciplinary team of specialists come together to deliver care for solid tumors.