Liposarcoma is a malignant soft tissue tumor that develops
in fat tissue. It’s most often found in the abdominal cavity or extremities,
usually the thigh or upper arm, but it can be found anywhere in the body.
Children with liposarcoma are treated at Dana-Farber/Boston Children's through our Bone and Soft Tissue Program. Our integrated pediatric oncology program offers the
combined expertise of a leading cancer center and a world-renown children’s
Because soft tissue sarcomas affect tissue that is elastic
and easily moved, a tumor may exist for a long time before being discovered,
growing large and pushing aside surrounding tissue. Liposarcoma symptoms vary greatly with
the size, location and spread of the tumor, but may include:
In addition to a physical examination, a doctor may order
the following to diagnose a liposarcoma:
After all tests are completed, doctors will be able to
outline the best treatment options.
The treatment of liposarcoma depends on how far the disease has spread and how aggressive it is. Standard treatment is surgery to remove the entire tumor along with surrounding healthy tissue to ensure that no cancer cells remain. Radiation therapy and chemotherapy are used only if surgery alone is ineffective.
Treatment for recurrent liposarcoma
Local recurrence of the disease following surgical resection is common and may be avoided with adjuvant radiation therapy. The risk of recurrence increases with high-grade tumors.
Survival rates for liposarcoma vary widely, depending on the subtype. Myxoid tumors have a five-year survival rate of 80 percent, while aggressive pleomorphic tumors can have a five-year survival rate closer to 20 percent.
Children treated for liposarcoma should visit a cancer survivorship clinic every year to:
A typical follow-up visit may include some or all
of the following:
Through our David B. Perini, Jr. Quality of Life Clinic, childhood cancer survivors receive a comprehensive follow-up evaluation from their cancer care team. In addition to meeting with your pediatric
oncologists, your child may see one of our endocrinologists, cardiologists,
neurologists, neuro-psychologists or alternative/complementary therapy
Phone: 617-632-5508Online form: Request an appointment
Katherine Janeway, MD, talks about caring for children with solid tumors. She is always inspired by the resilience of children with cancer, and their families.