Lisa R. Diller, MD

Chief Medical Officer, Dana-Farber/Boston Children's Cancer and Blood Disorders Center

Clinical Director, Pediatric Oncology

Medical Director, Clinical Cancer and Blood Disorders Service Line

Medical Director, David B. Perini, Jr. Quality of Life Clinic

Institute Physician

Professor of Pediatrics, Harvard Medical School
Office Phone: 617-632-5642
Appointment Phone: 888-733-4662 (new), 617-632-3270 (established)
Fax: 617-582-9049
Preferred Contact Method: office phone

General

Treatment Centers
Discipline
Pediatric Hematology/Oncology
Clinical Interests
Cancer predisposition, Global health, Late effects of pediatric cancer, Melanoma, Neuroblastoma, Retinoblastoma, Solid tumors, Wilms tumor

Location

Dana-Farber Cancer Institute
450 Brookline Avenue
Boston, MA  02215

Background

Board Certifications
Pediatric Hematology/Oncology
Pediatrics
Fellowships
Boston Children's Hospital/Dana-Farber Cancer Institute, Pediatric Hematology/Oncology
Residency
Boston Children's Hospital, Pediatrics
Internships
Children's Hospital Boston
Medical School
University of California, San Diego School of Medicine, 1985
Biography

Dr. Lisa Diller is the Chief Medical Officer, Dana-Farber/Boston Children's Cancer and Blood Disorders Center. As a pediatric oncologist and the Clinical Director of Pediatric Oncology, she leads the joint clinical Pediatric Oncology Program at the Dana-Farber Cancer Institute and Boston Children's Hospital. She is also the Director of the Perini Family Survivors Center and the David B. Perini, Jr. Quality of Life Clinic for Cancer Survivors at Dana-Farber. She is a Professor of Pediatrics at Harvard Medical School. Dr. Diller received a bachelors degree from Harvard University, and earned her medical degree from the University of California at San Diego. She was a resident at Boston Children's Hospital and did her subspecialty training at Boston Children's Hospital/Dana-Farber Institute where she has been on the faculty for more than 20 years. Dr. Diller's research focuses on the late effects of treatment for childhood cancer and genetic cancer predisposition syndromes in childhood. In addition, she investigates novel treatments for pediatric solid tumors, particularly tumors that occur in infants and toddlers.

Research
Neuroblastoma and Cancer Survivorship

The focus of our research is in two major areas: the treatment of patients with solid tumors - notably neuroblastoma and Wilms' tumor - and the study of survivors of childhood cancer.In treating patients with neuroblastoma, our approach has been to intensify therapy using high-dose therapy in tandem with stem cell rescue. In addition, we are studying new approaches to the treatment of minimal residual neuroblastoma, including antiangiogenic agents, demethylating agents, and immunomodulatory approaches. (We are participants in the New Agents in Neuroblastoma Therapy consortium.) Studies of survivors of neuroblastoma are also under way. In research on medical late effects, we have been studying young adult patients with a history of cancer treatment, hoping to delineate the morbidity of a variety of therapies and to introduce screening and prevention in this group of patients. We also have completed an early mammography trial after chest irradiation, showing that women who were treated with chest radiation are at significant risk of breast cancer and that mammography detects early tumors in this cohort. A prevention trial using tamoxifen for these women is in analysis. Moreover, we are active participants in the largest childhood cancer survivor cohort study, the Childhood Cancer Survivor Study, involving 24 centers and over 17,000 survivors. We have completed an analysis of breast cancers in that cohort, and are studying risk factors for secondary sarcomas. Interventional studies using the same cohort are under way, including a web-based smoking cessation intervention, an analysis of breast cancer screening behaviors, and a planned study of renal disease screening.

Video: Meet Video 1

Appointments & Second Opinions

Speak with one of our New Patient Coordinators to schedule an appointment, refer a patient or request a second opinion. In urgent cases, we can typically see new patients within 24 hours.

Clinical Trials

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Harvard Medical Affiliate

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As a teaching affiliate of Harvard Medical School, our physicians are passing on their expertise to the next generation of pediatric hematologists and oncologists.