• CAR T-Cell Therapy for Pediatric Leukemia


    CAR (chimeric antigen receptor) T-cell therapy is a promising new treatment for some of the most challenging cases we face in pediatric acute lymphoblastic leukemia (ALL). It works by modifying the body's T-cells, a type of immune system cell that hunts and destroys abnormal cells, such as cancer cells.

    Learn more about CAR T-cell therapy.

    Who is Eligible for KYMRIAH?

    Dana-Farber/Boston Children's is a certified treatment center for providing the FDA-approved CAR T-cell therapy, KYMRIAH, to patients who are up to 25 years old with second or later relapsed or refractory B-cell acute lymphoblastic leukemia (ALL).

    We are committed to finding the best treatment for our patients. We evaluate each patient individually to determine a personalized treatment plan. This may include CAR T-cell therapy, stem cell transplant, clinical trials, or a combination of these therapies. To determine the best treatment course for a patient, we evaluate factors including the biology of the patient’s cancer, the time of relapse, and patient-specific attributes like age. For example, the best treatment plan for one patient may be using CAR T-cell therapy as a bridge to a stem cell transplant, and for another, it may be only a stem cell transplant.

    Get answers to frequently asked questions about KYMRIAH and CAR T-cell therapy.

    For more information about whether KYMRIAH is right for your child or to refer a patient, contact:

    Colleen Dansereau, RN
    Director of Clinical Operations, Gene Therapy Program
    Phone: 617-919-7008
    Email: colleen.dansereau@childrens.harvard.edu

  • Contact Us

    Our specialized new patient coordinators can answer your questions about treatment options and becoming a patient.
  • How Does CAR T-Cell Therapy Work?

  • Having a Ball After CAR T-Cell Therapy

    cole-malone-thumbAfter undergoing a promising new treatment for acute lymphoblastic leukemia (ALL), Cole Malone is back to doing what he loves: playing on a flag football team with his twin brother, Michael.

  • Find Clinical Trials

    We sponsor and collaborate on clinical trials that break new ground in pediatric cancer and blood disorder treatment. callout bg