• The CAR T-Cell Therapy Team

    A specialized team of caregivers will guide you through the CAR T-cell process. Members of the team will include:

    Lewis B. Silverman, MD
    Director of Clinical Research and Clinical Care, Department of Pediatric Oncology
    Dr. Silverman's major research focus is in childhood acute lymphoblastic leukemia (ALL). He is the principal investigator of the DFCI ALL Consortium, a multi-institutional group conducting clinical trials in children with newly diagnosed and relapsed ALL. Dr. Silverman designs and oversees these studies, which have yielded high cure rates for children with newly diagnosed ALL. His research is also focused on reducing short- and long-term effects of treatment in pediatric ALL patients, as well as testing novel therapies in patients with relapsed disease.

    Alessandra Biffi, MD
    Co-Director, Gene Therapy Program
    Dr. Biffi is an internationally known gene therapy research leader from Milan, Italy. As co-director of the Gene Therapy Program, she is working to extend gene therapy treatments to new diseases and is actively involved in clinical trials for genetic diseases.

    Steven P. Margossian, MD, PhD
    Senior Physician, Stem Cell Transplant Center
    Dr. Margossian is a member of one of the largest pediatric stem cell transplant centers in the country and excels at helping children and families adjust during diagnosis and treatment. His role as a physician and a researcher allows him to be on the leading edge of both clinical research and patient care.

    Andrew E. Place, MD, PhD
    Clinical Director, Pediatric Hematologic Malignancy Center
    Dr. Place is a physician-scientist in the Hematologic Malignancy Program. His clinic expertise focuses on the treatment of children and adolescents with high-risk leukemias and lymphomas. With an intent to improve outcomes for these patients, Dr. Place is pioneering new and effective treatments through high-impact clinical trials.

    Colleen Dansereau, RN, MSN, CPN
    Director of Clinical Operations, Gene Therapy Program
    As operations director of the Gene Therapy Program, Colleen administratively manages the CAR T-cell therapy program as well as all administrative responsibility for all of the gene therapy clinical trials that take place at Dana-Farber/Boston Children's, for conditions including sickle cell disease, Wiskott-Aldrich Syndrome (WAS), and chronic granulomatous disease (CGD).

    Nurse Navigators: Robyn Blacken, BSN, RN, CPHON, BMTCN and Brenda MacKinnon, BSN, RN
    Robyn and Brenda are the two nurse navigators that will guide you and your child through the entire treatment process. They both specialize in treating children with cancer and blood disorders. From collecting your child's T-cells through apheresis to infusion of the modified cells, they will be with you each step of the way to support you and make the process as smooth as possible.

    Psychosocial support team
    Our care team includes physicians, social workers, psychologists and psychiatrists. Each member of this team has special expertise in the social, emotional and psychological aspects of caring for children with cancer. We know that the whole family is affected by a cancer diagnosis so we provide care and support for each family member throughout each stage of the treatment journey.