The Pediatric Cancer Genetic Risk Program at Dana-Farber/Boston
Children's provides cancer risk assessment for children, comprehensive
recommendations for managing cancer risk in children, and psychosocial support for
families affected by hereditary cancer. We also conduct research into many
aspects of cancer risk and its management. We are one of the few cancer genetic
risk programs in the U.S. focused specifically on pediatric cancer risk.
Our goal is to help you determine whether your children are at risk of
cancer – and if so, what can be done either to help prevent cancer in your
children or to catch it early and address it quickly for the best possible
outcome.
We help you manage all aspects of genetic cancer risk – from consideration
of testing to monitoring to counseling. A visit to our program
usually includes time with both a physician and a genetic counselor, both of
whom have expertise in inherited cancer syndromes that affect children. We
are also one of the few programs of this type that includes a pediatric
psychologist who specializes in pediatric hereditary cancer. This
specialized consultation is a standard part of clinic visits offered to each
family.
We also provide consultation to
community-based providers who may be unfamiliar with the unique medical and psychosocial
issues that arise when a family receives a hereditary cancer diagnosis.
If
you or your doctor believe your child might have an inherited form of cancer or
be at increased risk for developing cancer – or if you are considering having
children and want to better understand possible risk for your children – you
may wish to schedule an appointment with us.
Our program is recommended for children who have:
- A diagnosis or prior treatment for a rare
childhood cancer or brain tumor
- A diagnosis or prior treatment for a cancer of
any type plus a family history of cancer
- A strong family history of cancer
- A parent (or another relative) known to have a
cancer syndrome or a cancer gene mutation
The field of genetics is rapidly changing, and we provide advanced options in
genetic testing across the spectrum of new and established inherited cancer
syndromes. The syndromes include, but are not limited to:
- Cowden syndrome
- DICER1 syndrome
- Familial Adenomatous Polyposis
- Hereditary retinoblastoma
- Li-Fraumeni syndrome
- Multiple Endocrine Neoplasia
- Pheochromocytoma/paragangliglioma syndrome
- Von Hippel-Lindau syndrome
Although our Pediatric Cancer Genetic Risk Program is focused on pediatric cancer risk,
adult family members may choose to visit the Dana-Farber Center for Cancer Genetics and Prevention. Both programs work
closely together, allowing us to provide integrated care for families.
Our team includes pediatric oncologists,
genetic counselors, psychologists, and other specialists from the Dana-Farber/Boston
Children’s Cancer and Blood Disorders Center, the Center for Cancer Genetics and Prevention at
Dana-Farber Cancer Institute, and the Division of Genetics at Boston Children's
Hospital.
The core clinical team at Dana-Farber/Boston Children’s includes:
- Lisa Diller, MD, Co-Director
and Pediatric Oncology Attending Physician
- Junne Kamihara, MD, PhD, Co-Director
and Pediatric Oncology Attending Physician
- Allison O’Neill, MD, Pediatric Oncology Attending
Physician
- Katherine A. Janeway, MD, MMSc, Pediatric
Oncology Attending Physician
- Katherine Schneider, MPH, CGC, Genetic
Counselor
- Jaclyn Schienda, ScM, CGC, Genetic Counselor
- Sarah Brand, PhD, Attending Psychologist
Most cases are reviewed by a larger multidisciplinary team composed
of genetic counselors, geneticists, pediatric specialists, psychologists, and
oncologists from Dana-Farber and Boston Children’s Hospital. This larger
team also forms the basis of expert referrals as needed and includes the
following specialists:
- Judy Garber, MD, MPH, Director, Center for Cancer Genetics and
Prevention, Dana-Farber Cancer Institute
- Huma Rana, MD, Clinical Director, Center
for Cancer Genetics and Prevention, Dana-Farber Cancer Institute
- Wen-Hann Tan, BMBS, Geneticist, Boston
Children’s Hospital
- David Miller, MD, PhD, Geneticist, Boston
Children’s Hospital
- Victor Fox, MD, Director, Center for
Pediatric Polyposis, Boston Children's Hospital
- Stephen Huang, MD, Director, Thyroid
Program, Boston Children's Hospital
- Pamela Hawley, MS, CGC, Genetic Counselor, Boston Children’s Hospital
- Stephanie (Newton) Coury, MS, CGC, Genetic Counselor, Boston Children’s Hospital
- Sharyn Lincoln, MS, CGC, Genetic Counselor, Boston Children’s Hospital
- Jill Brace O'Neill, MS, RN-CS, PNP, Pediatric Nurse Practitioner, Dana-Farber Cancer Institute
- Andrea Patenaude, PhD, Clinical Psychologist, Dana-Farber Cancer Institute
In recent years, researchers have made great strides in building our
understanding of how genetic factors influence cancer risk – and how we can
leverage new technologies for testing and screening. At the Pediatric Cancer
Genetic Risk Program, our comprehensive program includes not only the clinical
care of children with cancer but incorporates research at the forefront of
genetic discovery.
Some of our research interests include:
- Multiplex sequencing to identify hereditary cancer
risk in pediatric cancer patients
- Screening with whole body
MRI for detection of primary tumors in children and adults with Li-Fraumeni
Syndrome (LFS)
- Hereditary risk factors for thyroid cancer
- Support
for pediatric patients and families at risk of hereditary cancer
We offer appointments Monday-Friday. We will work with your
insurance company to obtain coverage; in most cases, insurance companies will
provide coverage.
Phone: 617-632-4298
Fax: 617-582-7434
Email: pedi_genetics@dfci.harvard.edu
Mailing
address:
450 Brookline Avenue
Dana Building, Rm. 3-122
Boston Ma, 02215
International
patients
Email pedi_international@dfci.harvard.edu,
call +1
617-632-2952, or visit our International Patient
Services web section to learn more about our
specialized services for international patients.