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Phase I Trial of Immunotherapy Opens for Children with Relapsed or Treatment-resistant Leukemia

May 11, 2015
Dana-Farber/Boston Children's has joined a clinical trial of immunotherapy for children with relapsed or treatment-resistant acute lymphoblastic leukemia (ALL). Led by Memorial Sloan Kettering Cancer Center, the trial is one of several nationally that are evaluating cancer immunotherapy, a treatment approach—hailed by Science magazine as their Breakthrough of the Year in 2013—that triggers a patient's immune system to attack his or her cancer cells.

Promising Drug Target Identified in Medulloblastoma

March 26, 2015
Scientists have identified a protein critical to both the normal development of the brain and, in many cases, the development of medulloblastoma, a fast-growing brain tumor that usually strikes children under 10 years of age. The findings point to Eya1 as a prime target for new drugs for this type of medulloblastoma, and for other cancers that share the same path of development.

The Late Effects of Childhood Cancer

March 02, 2015
“The [cancer] therapies that we use in children in order to cure them, especially very young children, can have a significant impact upon their health during childhood, adolescence and adulthood,” Lisa Diller, MD, tells Radio Health.

Five Things Pediatricians Should Know About Children Who’ve Had Cancer

February 17, 2015
Children who’ve had cancer can present challenges for primary care providers that range from early and late effects of treatment to emotional needs.

Palliative Care Eases the Burden of Serious Illness

February 16, 2015
Pediatric palliative care helps maximize quality of life for children with serious life-threatening or life-limiting illness.

Boston Hospitals Pave Way for Precision Medicine

February 05, 2015
President Obama’s proposed investment in precision medicine would help clinical researchers determine which targeted therapies are most important to study in children with cancer.

Cancer Care for the Developing World

February 02, 2015
Access to life-saving advances in treating adult and childhood cancer remains elusive in low- and middle-income countries, where the majority of cancer patients reside today.

Imaging Captures How Blood Stem Cells Take Root

January 15, 2015
A see-through zebrafish and enhanced imaging provide the first direct glimpse of how blood stem cells take root in the body to generate blood.

Family of Infant with AML Goes Home for Christmas

December 26, 2014
A baby born with acute myeloid leukemia on July 4 finally went home to Adams, MA, on Christmas Day after living with his parents in our inpatient unit at Boston Children’s Hospital.

Nine-year-old with Brain Tumor gets to Finish Concert with Friends

December 11, 2014
Sophie Fellows, a wispy 9-year-old Vermont girl with a love of the violin, was diagnosed with a brain tumor a day after she was stricken with a painful headache in the middle of a holiday concert in Vermont. A day before her surgery, her music teacher and fellow musicians joined Sophie at Boston Children’s Hospital to finish the concert, The Boston Globe reports.
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