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Young adult survivors of childhood cancer report overall health similar to middle-aged in general population

April 21, 2016
Do survivors of childhood cancer return to normal health as they grow up? According to new research published in the Journal of the National Cancer Institute, overall health-related quality of life in young adult survivors of childhood cancer resembles that of middle-aged adults.

Making a Difference

March 31, 2016
Venee Tubman, MD, has deep roots in Liberia, where her grandfather was the nation’s longest serving president. The pediatric hematologist/oncologist is bringing her expertise in sickle cell disease to the African country, where she has been instrumental in establishing newborn screening and follow-up care, Penn Medicine reports.

Amazing Allison: A young 'pioneer' and the Boston doctors who saved her

March 21, 2016
WBZ-TV anchor Lisa Hughes reports on a young brain tumor patient who became the first child on a targeted therapy trial for an adult skin cancer. Allison's tumors had stopped responding to treatment, but two months after starting the precision medicine, her tumors disappeared.

The Coalition for Pediatric Medical Research: Recommended Pediatric Priorities for the Cancer Moonshot Initiative

March 03, 2016
David A. Williams, MD, president of Dana-Farber/Boston Children's Cancer and Blood Disorders Center, and other members of the Coalition for Pediatric Medical Research met with the staff of Vice President Joseph Biden, leader of the federal government's cancer moonshot. The coalition members urged Biden's staff to ensure that pediatric cancer is represented on the moonshot and presented their recommendations.

Study explores how high-fat diet influences colon cancer

March 02, 2016
A study published in Nature reveals how a high-fat diet makes the cells of the intestinal lining more likely to become cancerous. The new study of mice suggests that a high-fat diet drives a population boom of intestinal stem cells and also generates a pool of other cells that behave like stem cells — that is, they can reproduce themselves indefinitely and differentiate into other cell types. These stem cells and "stem-like" cells are more likely to give rise to intestinal tumors.

Childhood leukemia patients from high-poverty areas more likely to suffer early relapse

February 23, 2016
Children with acute lymphoblastic leukemia (ALL) who live in high-poverty areas are substantially more likely to suffer early relapse than other patients, despite having received the same treatment. The findings are significant because ALL that relapses early is more difficult to successfully treat.

Genetic Cause Identified in Rare Pediatric Brain Tumor

February 01, 2016
Diagnosis and treatment decisions for a recently recognized type of children’s brain tumor should be improved by the discovery of the genetic mechanism that causes it, say researchers who identified the unusual DNA abnormality in angiocentric gliomas.

Genetic Sequencing Can Help Guide Treatment in Children with Solid Tumors

January 28, 2016
Clinical genomic sequencing is feasible in pediatric oncology and can be used to recommend therapy or pinpoint diagnosis in children with solid tumors, according to the multicenter Individualized CAncer Therapy (iCat) study. The study, published in JAMA Oncology, is one of the first of its kind to be conducted in pediatric oncology. Its findings represent a significant step in making molecularly targeted, personalized therapy available to children with cancer.

Special holiday concert features young violinist and surgeon who removed her brain tumor

December 11, 2015
Last year Sophie Fellows was diagnosed with a brain tumor after a headache kept her from finishing a holiday concert. She just returned for an anniversary holiday concert with her neurosurgeon.

Therapy Directed Against Platelets Does Not Significantly Reduce Painful Crises in Sickle Cell Disease

December 08, 2015
Treatment with the antiplatelet agent prasugrel does not significantly reduce the rate of pain crises or severe lung complications in children with sickle cell disease, according to a report published in the New England Journal of Medicine describing one of the largest and most geographically diverse international clinical trials on sickle cell disease to date.
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