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Almost 1/3 of Families of Children with Cancer Have Unmet Basic Needs During Treatment

September 23, 2015
Almost one-third of families whose children were being treated for cancer faced food, housing or energy insecurity and one-quarter lost more than 40 percent of household income, according to a new study from Dana-Farber/Boston Children’s. The study, which was published in the journal Pediatric Blood & Cancer, follows emerging research in pediatric oncology finding that low-income status predicts poor adherence to oral chemotherapy and decreased overall survival.

Boston Hospitals Pave Way for Precision Medicine

February 05, 2015
President Obama’s proposed investment in precision medicine would help clinical researchers determine which targeted therapies are most important to study in children with cancer.

Cancer Care for the Developing World

February 02, 2015
Access to life-saving advances in treating adult and childhood cancer remains elusive in low- and middle-income countries, where the majority of cancer patients reside today.

Children with Childhood Leukemia Benefit from Prophylactic Antibiotics

December 06, 2015
Prophylactic antibiotics significantly reduce the risk of serious bacterial infections in children during the critical first month of treatment for acute lymphoblastic leukemia (ALL), the most common childhood cancer, according to a U.S. and Canadian study led by investigators from Dana-Farber/Boston Children's. While the overall cure rate for ALL is high, about one to two percent of children with this diagnosis die during the first month of therapy from treatment complications, primarily infection-related.

Discussing Child’s Cancer Prognosis More Likely to Produce Peace of Mind and Decrease Anxiety in Parents

May 14, 2015
New findings show informing parents about their child’s cancer prognosis – even when the prognosis is less than favorable – is much more likely to give parents peace of mind and hope rather than increase their anxiety or cause them to become depressed. The study was to be presented at the American Society of Clinical Oncology annual meeting.

Disparities in Outcomes for Children with Rare Eye Cancer Suggest Unequal Access to Primary Care

October 05, 2015
Disparities in outcomes for children with retinoblastoma — a rare eye tumor usually discovered in routine pediatric check-ups — suggest unequal access to primary care, researchers from Dana-Farber/Boston Children’s report in a study published in the journal JAMA Pediatrics. Although virtually all the children in the study survived, Hispanic children and children who lived in disadvantaged areas were more likely to lose an eye due to late diagnosis.

Early Gene Therapy Results in Wiskott-Aldrich Syndrome Promising

December 06, 2015
Researchers reported promising preliminary outcomes for the first four children enrolled in a U.S. gene therapy trial for Wiskott-Aldrich syndrome (WAS), a life-threatening genetic blood and immune disorder, at the 57th annual meeting of the American Society of Hematology.

Five Things Pediatricians Should Know About Children Who’ve Had Cancer

February 17, 2015
Children who’ve had cancer can present challenges for primary care providers that range from early and late effects of treatment to emotional needs.

Gene Editing Study Reveals Possible "Achilles Heel" of Sickle Cell Disease

September 16, 2015
Researchers from Dana-Farber/Boston Children's, using CRISPR-based gene editing tools, have found that changes to a small stretch of DNA may circumvent the genetic defect behind sickle cell disease (SCD). The discovery, published in the journal Nature, creates a path for developing gene editing approaches for treating SCD and other hemoglobin disorders, such as thalassemia.

Imaging Captures How Blood Stem Cells Take Root

January 15, 2015
A see-through zebrafish and enhanced imaging provide the first direct glimpse of how blood stem cells take root in the body to generate blood.
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