Appointments and Second Opinions

Speak with one of our New Patient Coordinators to schedule an appointment, refer a patient or request a second opinion. In urgent cases, we can typically see new patients within 24 hours.

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Find Clinical Trials

We sponsor and collaborate on clinical trials that break new ground in pediatric cancer and blood disorder treatment. 

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Our Affiliations
HMS Affiliate

Dana-Farber/Boston Children's is a teaching affiliate of Harvard Medical School.

Our Affiliations

Holcombe E. Grier, MD

  • Distinguished Staff
  • Professor of Pediatrics, Emeritus, Harvard Medical School


Treatment Centers


Clinical Interests

Ewing sarcoma, Non-rhabdomyosarcoma soft tissue sarcoma (NRSTS), Osteosarcoma, Rhabdomyosarcoma



Board Certifications

  • Internal Medicine, 1980
  • Pediatric Hematology/Oncology, 1990
  • Pediatrics, 1983


  • Boston Children's Hospital/Dana-Farber Cancer Institute, Pediatric Hematology/Oncology


  • North Carolina Memorial Hospital


  • North Carolina Memorial Hospital

Medical School

  • University of Pennsylvania School of Medicine, 1976


Dr. Grier received his MD from the University of Pennsylvania in 1976, and then trained in pediatrics, internal medicine, and infectious disease at the University of North Carolina. He joined Dana-Farber Cancer Institute in 1984. He is a past president of the American Society of Pediatric Hematology/Oncology and is a member of the steering committee for Bone Tumors in the Children's Oncology Group.


Pediatric Sarcomas

At the Children's Oncology Group, we work on the design and implementation of studies regarding Ewing sarcoma, osteosarcoma, rhabdomyosarcoma, and other soft tissue sarcomas. The Children's Oncology Group is a consortium of cancer treatment centers across the United States, Canada, and other countries. Dr. Grier is an active member of the Bone Tumor Disease Committee and the Soft Tissue Sarcoma Committee of this group. As part of the Pediatric Solid Tumor Center at Dana-Farber/Boston Children's, we help organize laboratory and clinical cross talk. We are also involved in cancer survivor studies that focus on the late effects of chemotherapy. These studies are led by Dr. Lisa Diller at the David B. Perini Jr. Quality of Life Clinic at Dana-Farber Cancer Institute. In addition, we participate in a study of the best application of palliative care through our work with the Pediatric Advanced Care Team, led by Dr. Joanne Wolfe.